Version 5.4
Mus musculus Protein: Magt1
Summary
InnateDB Protein IDBP-253628.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Magt1
Protein Name magnesium transporter 1
Synonyms 2410001C15Rik; 2610529C04Rik; 2810482I07Rik; IAG2; IAP;
Species Mus musculus
Ensembl Protein ENSMUSP00000109196
InnateDB Gene IDBG-166710 (Magt1)
Protein Structure
UniProt Annotation
Function May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells. {ECO:0000269PubMed:15804357}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed at high levels in kidney, colon, heart and liver. Expressed at lower levels in intestine, spleen, brain and lung. {ECO:0000269PubMed:15804357}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015095 magnesium ion transmembrane transporter activity
Biological Process
GO:0015693 magnesium ion transport
GO:0045454 cell redox homeostasis
GO:0050890 cognition
Cellular Component
GO:0005886 plasma membrane
GO:0008250 oligosaccharyltransferase complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1914325
InterPro IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain
IPR021149 Oligosaccharyl transferase complex, subunit OST3/OST6
PFAM PF13098
PF13192
PF13462
PF13905
PF00085
PF04756
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CQY5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 67075
UniGene Mm.400913
RefSeq
MGI ID
MGI Symbol Magt1
OMIM
CCDS
HPRD
IMGT
EMBL AK010320 AK012185 AK013243 AK018623 AK136622 AK144696 BC003881 DQ000005
GenPept AAH03881 AAY18812 BAB26851 BAB28085 BAB28739 BAB31313 BAE23074 BAE26020

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca