InnateDB Protein
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IDBP-253699.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mogat1
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Protein Name
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monoacylglycerol O-acyltransferase 1
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Synonyms
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0610030A14Rik; 1110064N14Rik; Dgat2l; Dgat2l1; mDC2; MGAT1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000109152
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InnateDB Gene
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IDBG-172563 (Mogat1)
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Protein Structure
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Function |
Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine. {ECO:0000269PubMed:12077311}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000305PubMed:12077311}; Multi-pass membrane protein {ECO:0000305PubMed:12077311}.
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Disease Associations |
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Tissue Specificity |
Expressed at high level in kidney and stomach. Expressed at lower level in brown and white adipose tissue, uterus and liver. Not detected in small intestine. {ECO:0000269PubMed:12077311}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0003846
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2-acylglycerol O-acyltransferase activity
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GO:0004144
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diacylglycerol O-acyltransferase activity
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GO:0016747
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transferase activity, transferring acyl groups other than amino-acyl groups
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915643
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InterPro |
IPR007130
Diacylglycerol acyltransferase
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PFAM |
PF03982
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91ZV4
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PhosphoSite |
PhosphoSite-Q91ZV4
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TrEMBL |
Q3V4B0
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UniProt Splice Variant |
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Entrez Gene |
68393
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UniGene |
Mm.429219
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RefSeq |
XP_006496589
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MGI ID |
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MGI Symbol |
Mogat1
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OMIM |
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CCDS |
CCDS15085
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HPRD |
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IMGT |
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EMBL |
AC158559
AF384162
AK002693
AK004368
BC106135
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GenPept |
AAI06136
AAK84177
BAB22288
BAE43174
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