InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ddx43

Summary

InnateDB Protein

IDBP-254041.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Ddx43

Protein Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 43

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108994

InnateDB Gene

IDBG-186756 (Ddx43)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0008150	biological_process

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

MGI:3642857

InterPro

IPR001650 Helicase, C-terminal
IPR004087 K Homology domain
IPR004088 K Homology domain, type 1
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF00013
PF13014
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00322
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite