Mus musculus Protein: Cab39
Summary
InnateDB Protein IDBP-254059.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cab39
Protein Name calcium binding protein 39
Synonyms AA408805; AA960512; C78372; MO25; MO25alpha;
Species Mus musculus
Ensembl Protein ENSMUSP00000108987
InnateDB Gene IDBG-176216 (Cab39)
Protein Structure
UniProt Annotation
Function Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004674 protein serine/threonine kinase activity
GO:0005488 binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0030295 protein kinase activator activity
GO:0043539 protein serine/threonine kinase activator activity
Biological Process
GO:0006468 protein phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0023014 signal transduction by phosphorylation
GO:0032147 activation of protein kinase activity
GO:0035556 intracellular signal transduction
GO:0051291 protein heterooligomerization
GO:0071902 positive regulation of protein serine/threonine kinase activity
Cellular Component
GO:0005737 cytoplasm
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:107438
InterPro IPR013878 Mo25-like
IPR016024 Armadillo-type fold
PFAM PF08569
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q06138
PhosphoSite PhosphoSite-Q06138
TrEMBL Q8K312
UniProt Splice Variant
Entrez Gene 12283
UniGene Mm.427203
RefSeq NP_598542
MGI ID
MGI Symbol Cab39
OMIM
CCDS CCDS15112
HPRD
IMGT
EMBL AC107707 AC161342 AK144665 BC020041 BC029053 CH466520 S51858
GenPept AAB24801 AAH20041 AAH29053 BAE25997 EDL40253 EDL40254 EDL40256