Version 5.4
| Mus musculus Protein: Shq1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-254155.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Shq1 | ||||||||
| Protein Name | SHQ1 homolog (S. cerevisiae) | ||||||||
| Synonyms | 2810403P18Rik; Grim-1; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000108938 | ||||||||
| InnateDB Gene | IDBG-173007 (Shq1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA. {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm, cytosol {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Note=May at least partially shuttle between cytosol and nucleoplasm. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1919421 | ||||||||
| InterPro |
IPR007009
SHQ1 protein IPR007052 CS domain IPR008978 HSP20-like chaperone |
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| PFAM |
PF04925
PF04969 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q7TMX5 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 72171 | ||||||||
| UniGene | Mm.256022 | ||||||||
| RefSeq | XP_006506731 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Shq1 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK012978 BC052657 | ||||||||
| GenPept | AAH52657 | ||||||||