Version 5.4
Mus musculus Protein: B3gnt7
Summary
InnateDB Protein IDBP-254166.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3gnt7
Protein Name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000108931
InnateDB Gene IDBG-254164 (B3gnt7)
Protein Structure
UniProt Annotation
Function May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Strongly expressed in placenta and colon. Moderately expressed in lung, stomach, small intestine and kidney. Very weakly expressed in cerebrum, cerebellum, heart and testis. {ECO:0000269PubMed:12061784}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008375 acetylglucosaminyltransferase activity
GO:0008378 galactosyltransferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2384394
InterPro IPR002659 Glycosyl transferase, family 31
IPR003378 Fringe-like
PFAM PF01762
PF02434
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K0J2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 227327
UniGene Mm.86467
RefSeq NP_660257
MGI ID
MGI Symbol B3gnt7
OMIM
CCDS CCDS35645
HPRD
IMGT
EMBL AF502429 AK080081 AK131975 AK154691 BC031187 BC060507
GenPept AAH31187 AAH60507 AAM61769 BAC37824 BAE20915 BAE32766

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca