Version 5.4
Mus musculus Protein: Eng
Summary
InnateDB Protein IDBP-254241.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Eng
Protein Name endoglin
Synonyms AI528660; AI662476; CD105; Endo; S-endoglin;
Species Mus musculus
Ensembl Protein ENSMUSP00000108897
InnateDB Gene IDBG-160783 (Eng)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0003273 cell migration involved in endocardial cushion formation
GO:0007507 heart development
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0045766 positive regulation of angiogenesis
Cellular Component
Protein Structure and Domains
PDB ID MGI:95392
InterPro IPR001507 Zona pellucida domain
PFAM PF00100
PRINTS PR00023
PIRSF
SMART SM00241
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UAM9
UniProt Splice Variant
Entrez Gene 13805
UniGene Mm.225297
RefSeq NP_001139820
MGI ID
MGI Symbol Eng
OMIM
CCDS CCDS50570
HPRD
IMGT
EMBL AK151302 AL772271 EU330531
GenPept ABY49139 BAE30285

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca