Version 5.4
Mus musculus Protein: Cntn4
Summary
InnateDB Protein IDBP-254246.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cntn4
Protein Name contactin 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000108889
InnateDB Gene IDBG-173779 (Cntn4)
Protein Structure
UniProt Annotation
Function Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis. {ECO:0000269PubMed:9733924}.
Subcellular Localization Cell membrane; Lipid-anchor, GPI-anchor. Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in the region of developing olfactory neurons. Isoform 2 is expressed in mature sensory cells of the vomeronasal neuroepithelium and at lower level in olfactory neuroepithelium. {ECO:0000269PubMed:9733924}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007399 nervous system development
GO:0007420 brain development
GO:0031175 neuron projection development
GO:0045665 negative regulation of neuron differentiation
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID MGI:1095737
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
PFAM PF00041
PF01108
PF07679
PF07686
PF00047
PRINTS
PIRSF
SMART SM00408
SM00409
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q69Z26
PhosphoSite PhosphoSite-Q69Z26
TrEMBL
UniProt Splice Variant
Entrez Gene 269784
UniGene Mm.321683
RefSeq NP_001103219
MGI ID 3KLD
MGI Symbol Cntn4
OMIM
CCDS CCDS51866
HPRD
IMGT
EMBL AK036262 AK043507 AK173340 BC115766 X99043
GenPept AAI15767 BAC29365 BAC31563 BAD32618 CAA67504

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca