InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Drp2

Summary

InnateDB Protein

IDBP-254319.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Drp2

Protein Name

dystrophin related protein 2

Synonyms

AW495265; DRP-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108852

InnateDB Gene

IDBG-171136 (Drp2)

Protein Structure

UniProt Annotation

Function

Possibly involved in membrane-cytoskeleton interactions of the central nervous system. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

MGI:107432

InterPro

IPR000433 Zinc finger, ZZ-type
IPR001202 WW domain
IPR002017 Spectrin repeat
IPR015153 EF-hand domain, type 1
IPR015154 EF-hand domain, type 2
IPR017433 Dystrophin-related protein 2
IPR018159 Spectrin/alpha-actinin

PFAM

PF00569
PF00397
PF00435
PF09068
PF09069

PRINTS

PIRSF

PIRSF038205

SMART

SM00291
SM00456
SM00150

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt