Version 5.4
Mus musculus Protein: Hnrnph2
Summary
InnateDB Protein IDBP-254380.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hnrnph2
Protein Name heterogeneous nuclear ribonucleoprotein H2
Synonyms DXHXS1271E; Ftp-3; Ftp3; H\'; HNRNP; Hnrph2;
Species Mus musculus
Ensembl Protein ENSMUSP00000108828
InnateDB Gene IDBG-171611 (Hnrnph2)
Protein Structure
UniProt Annotation
Function This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG) (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 50 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID MGI:1201779
InterPro IPR000504 RNA recognition motif domain
IPR012996 Zinc finger, CHHC-type
PFAM PF00076
PF08080
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70333
PhosphoSite PhosphoSite-P70333
TrEMBL Q3UR26
UniProt Splice Variant
Entrez Gene 56258
UniGene Mm.476198
RefSeq
MGI ID
MGI Symbol Hnrnph2
OMIM
CCDS CCDS30397
HPRD
IMGT
EMBL AK077716 AK141861 AK164115 AK168116 AK169104 BC005461 U58105
GenPept AAB47243 AAH05461 BAC36976 BAE24862 BAE37634 BAE40087 BAE40886

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca