Version 5.4
Mus musculus Protein: Ralgps1
Summary
InnateDB Protein IDBP-254453.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ralgps1
Protein Name Ral GEF with PH domain and SH3 binding motif 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000108790
InnateDB Gene IDBG-162419 (Ralgps1)
Protein Structure
UniProt Annotation
Function Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeleton organization. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Associates with membranes through the PH domain. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:1922008
InterPro IPR001849 Pleckstrin homology domain
IPR001895 Guanine-nucleotide dissociation stimulator CDC25
IPR023578 Ras guanine nucleotide exchange factor, domain
PFAM PF00169
PF00617
PRINTS
PIRSF
SMART SM00233
SM00147
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-A2AR50
TrEMBL
UniProt Splice Variant
Entrez Gene 241308
UniGene Mm.473240
RefSeq XP_006498096
MGI ID
MGI Symbol Ralgps1
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca