Version 5.4
Homo sapiens Protein: FAM57B
Summary
InnateDB Protein IDBP-25446.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM57B
Protein Name family with sequence similarity 57, member B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000369863
InnateDB Gene IDBG-25444 (FAM57B)
Protein Structure
UniProt Annotation
Function Involved in ceramide synthesis. {ECO:0000250}.
Subcellular Localization Isoform 1: Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.Isoform 2: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0045599 negative regulation of fat cell differentiation
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006634 TRAM/LAG1/CLN8 homology domain
PFAM PF03798
PRINTS
PIRSF
SMART SM00724
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q71RH2
PhosphoSite PhosphoSite-Q71RH2
TrEMBL F1T0F5
UniProt Splice Variant
Entrez Gene 83723
UniGene Hs.736831
RefSeq NP_113666
HUGO HGNC:25295
OMIM 615175
CCDS CCDS10667
HPRD
IMGT
EMBL AB593089 AB593090 AF370365 AL136777 BC007892 CH471238
GenPept AAH07892 AAQ15201 BAJ84029 BAJ84030 CAB66711 EAW79938

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca