InnateDB Protein
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IDBP-254511.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gprasp1
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Protein Name
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G protein-coupled receptor associated sorting protein 1
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Synonyms
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2210415K24Rik; 3110031O14Rik; C87852; GASP; GASP1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000108770
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InnateDB Gene
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IDBG-172647 (Gprasp1)
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Protein Structure
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Function |
Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN1P1/BECN2. {ECO:0000269PubMed:23954414}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in the brain, with higher expression in the hippocampus, hypothalamus and olfactory bulb. {ECO:0000269PubMed:15086532}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1917418
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InterPro |
IPR006911
Armadillo repeat-containing domain
IPR016024
Armadillo-type fold
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PFAM |
PF04826
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q5U4C1
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PhosphoSite |
PhosphoSite-Q5U4C1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
67298
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UniGene |
Mm.475515
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RefSeq |
NP_001005385
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MGI ID |
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MGI Symbol |
Gprasp1
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OMIM |
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CCDS |
CCDS30409
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HPRD |
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IMGT |
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EMBL |
AB093241
AK039156
AK050919
AK083192
AL683822
BC027187
BC085157
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GenPept |
AAH27187
AAH85157
BAC30259
BAC34459
BAC38803
BAC41425
CAM27375
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