Version 5.4
Mus musculus Protein: G3bp2
Summary
InnateDB Protein IDBP-254527.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol G3bp2
Protein Name GTPase activating protein (SH3 domain) binding protein 2
Synonyms AA409541; E430034L04Rik; G3BP; mKIAA0660;
Species Mus musculus
Ensembl Protein ENSMUSP00000108752
InnateDB Gene IDBG-179407 (G3bp2)
Protein Structure
UniProt Annotation
Function Probable scaffold protein that may be involved in mRNA transport. {ECO:0000305}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006810 transport
GO:0007264 small GTPase mediated signal transduction
GO:0051028 mRNA transport
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2442040
InterPro IPR000504 RNA recognition motif domain
IPR002075 Nuclear transport factor 2
IPR018222 Nuclear transport factor 2, eukaryote
PFAM PF00076
PF02136
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P97379
PhosphoSite PhosphoSite-P97379
TrEMBL Q5DU21
UniProt Splice Variant
Entrez Gene 23881
UniGene Mm.290530
RefSeq NP_001074264
MGI ID
MGI Symbol G3bp2
OMIM
CCDS CCDS39149
HPRD
IMGT
EMBL AF145285 AK076117 AK145697 AK151965 AK169571 AK220349 BC048176 BC119806 BC122883 CH466617 U65313
GenPept AAC53553 AAD51933 AAH48176 AAI19807 AAI22884 BAC36197 BAD90412 BAE26595 BAE30836 BAE41234 EDL05270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca