InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cxcl9

Summary

InnateDB Protein

IDBP-254609.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cxcl9

Protein Name

chemokine (C-X-C motif) ligand 9

Synonyms

BB139920; CMK; crg-10; Mig; MuMIG; Scyb9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108716

InnateDB Gene

IDBG-179870 (Cxcl9)

Protein Structure

UniProt Annotation

Function

May be a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	1 [view]
Protein-DNA	6 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008009	chemokine activity
GO:0048248	CXCR3 chemokine receptor binding

Biological Process

GO:0006935	chemotaxis
GO:0006954	inflammatory response
GO:0006955	immune response
GO:0030816	positive regulation of cAMP metabolic process
GO:0042127	regulation of cell proliferation
GO:0043950	positive regulation of cAMP-mediated signaling
GO:0045087	innate immune response (InnateDB)
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
GO:0051607	defense response to virus
GO:0060326	cell chemotaxis