Version 5.4
Mus musculus Protein: Ggta1
Summary
InnateDB Protein IDBP-254792.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ggta1
Protein Name glycoprotein galactosyltransferase alpha 1, 3
Synonyms alpha3GalT; AW108479; Gal; GALT; Ggta; Ggta-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000108626
InnateDB Gene IDBG-164632 (Ggta1)
Protein Structure
UniProt Annotation
Function Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose- alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3). {ECO:0000269PubMed:12626403}.
Subcellular Localization Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016758 transferase activity, transferring hexosyl groups
GO:0046872 metal ion binding
GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0033580 protein galactosylation at cell surface
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031985 Golgi cisterna
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID MGI:95704
InterPro IPR005076 Glycosyl transferase, family 6
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF03414
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P23336
PhosphoSite PhosphoSite-P23336
TrEMBL Q3TXW0
UniProt Splice Variant
Entrez Gene 14594
UniGene Mm.480642
RefSeq NP_001139293
MGI ID
MGI Symbol Ggta1
OMIM
CCDS CCDS50576
HPRD
IMGT
EMBL AF297609 AF297610 AF297611 AF297612 AF297613 AF297614 AF297615 AK159087 M26925 M85153
GenPept AAA37657 AAA37711 AAK97205 AAK97206 BAE34805

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca