InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kynu

Summary

InnateDB Protein

IDBP-255158.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Kynu

Protein Name

kynureninase (L-kynurenine hydrolase)

Synonyms

4432411A05Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108445

InnateDB Gene

IDBG-167886 (Kynu)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0030170	pyridoxal phosphate binding
GO:0030429	kynureninase activity

Biological Process

GO:0006569	tryptophan catabolic process
GO:0008152	metabolic process
GO:0009435	NAD biosynthetic process
GO:0019805	quinolinate biosynthetic process
GO:0034354	'de novo' NAD biosynthetic process from tryptophan
GO:0043420	anthranilate metabolic process
GO:0097053	L-kynurenine catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:1918039

InterPro

IPR000192 Aminotransferase, class V/Cysteine desulfurase
IPR010111 Kynureninase
IPR015424 Pyridoxal phosphate-dependent transferase

PFAM

PF00266

PRINTS

PIRSF

PIRSF038800

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q6NSV5

UniProt Splice Variant

Entrez Gene

70789

UniGene

Mm.105278

RefSeq

NP_001276522

MGI ID

MGI Symbol

Kynu

OMIM

CCDS

HPRD

IMGT

EMBL

AL845160 AL845336 BC069848

GenPept

AAH69848