Version 5.4
Homo sapiens Protein: ZNF317
Summary
InnateDB Protein IDBP-25521.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF317
Protein Name zinc finger protein 317
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000247956
InnateDB Gene IDBG-25519 (ZNF317)
Protein Structure
UniProt Annotation
Function May function as a transcription factor. May play an important role in erythroid maturation and lymphoid proliferation.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Isoform 1 and isoform 2 are ubiquitously expressed. Isoform 3 and isoform 4 are expressed only in lymphocytes, spleen and lung. {ECO:0000269PubMed:11688974}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 10 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96PQ6
PhosphoSite PhosphoSite-Q96PQ6
TrEMBL A0A024R7B1
UniProt Splice Variant
Entrez Gene 57693
UniGene Hs.652645
RefSeq NP_065984
HUGO HGNC:13507
OMIM 613864
CCDS CCDS12210
HPRD 11706
IMGT
EMBL AB046808 AF148135 AF275255 AF307096 AF307097 BC078154 CH471106
GenPept AAH78154 AAL29182 AAL29188 AAL29190 AAL29191 BAB13414 EAW84011 EAW84014

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca