Version 5.4
Mus musculus Protein: Mbd5
Summary
InnateDB Protein IDBP-255338.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mbd5
Protein Name methyl-CpG binding domain protein 5
Synonyms 9430004D19Rik; AA536666; AI426407; C030040A15Rik; Gm1630; OTTMUSG00000012483;
Species Mus musculus
Ensembl Protein ENSMUSP00000108374
InnateDB Gene IDBG-168652 (Mbd5)
Protein Structure
UniProt Annotation
Function Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro) (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Associated with pericentric heterochromatin. {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:20700456}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
Biological Process
GO:0040014 regulation of multicellular organism growth
GO:0042593 glucose homeostasis
GO:0060399 positive regulation of growth hormone receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
Protein Structure and Domains
PDB ID MGI:2138934
InterPro IPR001739 Methyl-CpG DNA binding
IPR016177 DNA-binding domain
PFAM PF01429
PRINTS
PIRSF
SMART SM00391
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt B1AYB6
PhosphoSite PhosphoSite-B1AYB6
TrEMBL
UniProt Splice Variant
Entrez Gene 109241
UniGene Mm.444746
RefSeq NP_001277585
MGI ID
MGI Symbol Mbd5
OMIM
CCDS CCDS71051
HPRD
IMGT
EMBL AL845298 BC138375 BC138378 BX546465
GenPept AAI38376 AAI38379 CAM16085 CAM19541

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca