InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Spp1

Summary

InnateDB Protein

IDBP-255348.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Spp1

Protein Name

secreted phosphoprotein 1

Synonyms

2AR; Apl-1; BNSP; Bsp; BSPI; Eta; ETA-1; OP; Opn; Opnl; Ric; Spp-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108366

InnateDB Gene

IDBG-185485 (Spp1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 76 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	3 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	76 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0050840	extracellular matrix binding

Biological Process

GO:0001503	ossification
GO:0001649	osteoblast differentiation
GO:0006954	inflammatory response
GO:0007155	cell adhesion
GO:0010811	positive regulation of cell-substrate adhesion
GO:0030593	neutrophil chemotaxis
GO:0033280	response to vitamin D
GO:0045087	innate immune response (InnateDB)
GO:0045780	positive regulation of bone resorption
GO:0048545	response to steroid hormone
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury

Cellular Component

GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0031988	membrane-bounded vesicle
GO:0042995	cell projection
GO:0045177	apical part of cell
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:98389

InterPro

IPR002038 Osteopontin

PFAM

PF00865

PRINTS

PR00216

PIRSF

SMART

SM00017

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z513

UniProt Splice Variant

Entrez Gene

20750

UniGene

Mm.470561

RefSeq

MGI ID

MGI Symbol

Spp1

OMIM

CCDS

HPRD

IMGT

EMBL

AC124106

GenPept