InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Golga3

Summary

InnateDB Protein

IDBP-255855.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Golga3

Protein Name

golgi autoantigen, golgin subfamily a, 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108131

InnateDB Gene

IDBG-189422 (Golga3)

Protein Structure

UniProt Annotation

Function

Plays an important role in spermatogenesis and/or testis development. Probably identical with the serologically detectable male antigen (SDM). Probably involved in maintaining Golgi structure. {ECO:0000269PubMed:11835574}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Golgi apparatus, Golgi stack membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in testis. Transcripts can be found in spermatids during spermatogenesis. No expression in Leydig cells, spermatogonia or spermatocytes. Detected at low levels in all tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0030154	cell differentiation

Cellular Component

GO:0000139	Golgi membrane
GO:0005634	nucleus
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
GO:0017119	Golgi transport complex
GO:0032580	Golgi cisterna membrane
GO:0090498	extrinsic component of Golgi membrane