InnateDB Protein
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IDBP-256431.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gpm6b
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Protein Name
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glycoprotein m6b
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Synonyms
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AI593561; Gpm6; M6B;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000107854
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InnateDB Gene
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IDBG-185221 (Gpm6b)
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Protein Structure
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Function |
May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. {ECO:0000269PubMed:18581270}.
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Subcellular Localization |
Membrane; Multi-pass membrane protein. Cell membrane. Note=Colocalizes with SERT at the plasma membrane.
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Disease Associations |
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Tissue Specificity |
Widely expressed. In the brain, expressed in neurons and oligodendrocytes. {ECO:0000269PubMed:11749036}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:107672
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InterPro |
IPR001614
Myelin proteolipid protein PLP
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PFAM |
PF01275
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PRINTS |
PR00214
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PIRSF |
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SMART |
SM00002
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TIGRFAMs |
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Modification |
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SwissProt |
P35803
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PhosphoSite |
PhosphoSite-P35803
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TrEMBL |
Q3V0Z9
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UniProt Splice Variant |
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Entrez Gene |
14758
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UniGene |
Mm.474051
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RefSeq |
NP_001171432
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MGI ID |
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MGI Symbol |
Gpm6b
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OMIM |
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CCDS |
CCDS53243
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HPRD |
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IMGT |
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EMBL |
AF254869
AF254870
AF254871
AF254872
AF254873
AF254874
AF254875
AF254876
AF254877
AF254878
AF254879
AK016567
AK132778
AL671905
BC003912
BC025165
S65737
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GenPept |
AAB28351
AAF87987
AAF87988
AAF87989
AAF87990
AAF87991
AAF87992
AAF87993
AAF87994
AAF87995
AAF87996
AAF87997
AAH03912
AAH25165
BAB30309
BAE21354
CAM18328
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