Mus musculus Protein: Frmpd4 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-256617.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Frmpd4 | ||||||
Protein Name | FERM and PDZ domain containing 4 | ||||||
Synonyms | |||||||
Species | Mus musculus | ||||||
Ensembl Protein | ENSMUSP00000107777 | ||||||
InnateDB Gene | IDBG-185601 (Frmpd4) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | Positive regulator of dendritic spine morphogenesis and density (By similarity). Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5- bisphosphate (By similarity). {ECO:0000250}. | ||||||
Subcellular Localization | Cell projection, dendritic spine {ECO:0000250}. | ||||||
Disease Associations | |||||||
Tissue Specificity | Expressed in various regions of the brain, including cortex, hippocampus, cerebellum, olfactory bulb and medial habenular nucleus. {ECO:0000269PubMed:19118189}. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | MGI:3042378 | ||||||
InterPro |
IPR000299
FERM domain IPR001202 WW domain IPR001478 PDZ domain IPR019748 FERM central domain IPR019749 Band 4.1 domain IPR029071 Ubiquitin-related domain |
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PFAM |
PF00397
PF00595 PF13180 PF00373 |
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PRINTS | |||||||
PIRSF | |||||||
SMART |
SM00456
SM00228 SM00295 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | A2AFR3 | ||||||
PhosphoSite | PhosphoSite-A2AFR3 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 333605 | ||||||
UniGene | Mm.426168 | ||||||
RefSeq | XP_006528946 | ||||||
MGI ID | |||||||
MGI Symbol | Frmpd4 | ||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AK122244 AK147370 AK147440 AL672186 AL807744 AL807773 BC139429 BX546498 | ||||||
GenPept | AAI39430 BAC65526 BAE27868 BAE27913 CAM16366 CAM17768 CAM17769 CAM17770 CAM18047 CAM18048 CAM18049 CAM24062 | ||||||