Version 5.4
Mus musculus Protein: Foxm1
Summary
InnateDB Protein IDBP-256631.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Foxm1
Protein Name forkhead box M1
Synonyms AA408308; AW554517; BB238854; Fkh16; Foxm1b; HFH-11B; MPHOSPH2; Mpm2; WIN;
Species Mus musculus
Ensembl Protein ENSMUSP00000107776
InnateDB Gene IDBG-191010 (Foxm1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0008134 transcription factor binding
GO:0008301 DNA binding, bending
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001570 vasculogenesis
GO:0001889 liver development
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007389 pattern specification process
GO:0008284 positive regulation of cell proliferation
GO:0009888 tissue development
GO:0032873 negative regulation of stress-activated MAPK cascade
GO:0042127 regulation of cell proliferation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046578 regulation of Ras protein signal transduction
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
GO:0071156 regulation of cell cycle arrest
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:1347487
InterPro IPR001766 Transcription factor, fork head
PFAM PF00250
PRINTS PR00053
PIRSF
SMART SM00339
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q7Y0
UniProt Splice Variant
Entrez Gene 14235
UniGene Mm.42148
RefSeq
MGI ID
MGI Symbol Foxm1
OMIM
CCDS
HPRD
IMGT
EMBL AC116573
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca