Version 5.4
Mus musculus Protein: Hccs
Summary
InnateDB Protein IDBP-256689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hccs
Protein Name holocytochrome c synthetase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000107743
InnateDB Gene IDBG-185903 (Hccs)
Protein Structure
UniProt Annotation
Function Links covalently the heme group to the apoprotein of cytochrome c. {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004408 holocytochrome-c synthase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Protein Structure and Domains
PDB ID MGI:106911
InterPro IPR000511 Cytochrome c/c1 haem-lyase
PFAM PF01265
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P53702
PhosphoSite PhosphoSite-P53702
TrEMBL
UniProt Splice Variant
Entrez Gene 15159
UniGene Mm.414299
RefSeq XP_006528766
MGI ID
MGI Symbol Hccs
OMIM
CCDS CCDS30535
HPRD
IMGT
EMBL AL805974 AL831750 BC061466 BC062905 U36788
GenPept AAB19008 AAH61466 AAH62905 CAM22605

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca