Version 5.4
Mus musculus Protein: Plekha3
Summary
InnateDB Protein IDBP-257099.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plekha3
Protein Name pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
Synonyms FAPP1;
Species Mus musculus
Ensembl Protein ENSMUSP00000107551
InnateDB Gene IDBG-182237 (Plekha3)
Protein Structure
UniProt Annotation
Function Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P) (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005543 phospholipid binding
GO:0005545 1-phosphatidylinositol binding
Biological Process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1932515
InterPro IPR001849 Pleckstrin homology domain
PFAM PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ERS4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 83435
UniGene Mm.41636
RefSeq NP_112546
MGI ID
MGI Symbol Plekha3
OMIM
CCDS CCDS16162
HPRD
IMGT
EMBL AF286163 BC031110
GenPept AAG15200 AAH31110

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca