Version 5.4
Mus musculus Protein: Gsg1
Summary
InnateDB Protein IDBP-257127.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gsg1
Protein Name germ cell-specific gene 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000107542
InnateDB Gene IDBG-194583 (Gsg1)
Protein Structure
UniProt Annotation
Function May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum. {ECO:0000269PubMed:18325338}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:18325338}; Multi-pass membrane protein {ECO:0000269PubMed:18325338}. Note=Colocalizes with PAPOLB in the endoplasmic reticulum.
Disease Associations
Tissue Specificity Expressed in spermatogenic cells (at protein level). Expressed in germ cells within the testis from day 21 onwards. {ECO:0000269PubMed:18325338, ECO:0000269PubMed:7957958}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0070063 RNA polymerase binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1194499
InterPro IPR004031 PMP-22/EMP/MP20/Claudin superfamily
IPR012478 GSG1-like
PFAM PF00822
PF13903
PF07803
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R1W2
PhosphoSite PhosphoSite-Q8R1W2
TrEMBL
UniProt Splice Variant
Entrez Gene 14840
UniGene Mm.272306
RefSeq NP_034482
MGI ID
MGI Symbol Gsg1
OMIM
CCDS CCDS39683
HPRD
IMGT
EMBL AC122820 AK006326 AK088285 BC023009 D87325
GenPept AAH23009 BAA37087 BAB24527 BAC40258

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca