InnateDB Protein
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IDBP-257199.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Arpp21
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Protein Name
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cyclic AMP-regulated phosphoprotein, 21
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Synonyms
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0710001E13Rik; AI853636; ARPP-21; D9Bwg1012e; R3hdm3; Tarpp;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000107503
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InnateDB Gene
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IDBG-202918 (Arpp21)
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Protein Structure
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Function |
Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons. {ECO:0000269PubMed:15499021}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:11298339, ECO:0000269PubMed:15096520}.
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Disease Associations |
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Tissue Specificity |
Isoform 1 is present at high levels in thymus and low levels in brain. In thymus, isoform 1 is specifically found in immature thymocytes (at protein level). {ECO:0000269PubMed:11298339}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:107562
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InterPro |
IPR001374
Single-stranded nucleic acid binding R3H
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PFAM |
PF01424
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PRINTS |
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PIRSF |
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SMART |
SM00393
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TIGRFAMs |
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Modification |
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SwissProt |
Q9DCB4
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PhosphoSite |
PhosphoSite-Q9DCB4
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TrEMBL |
E0CYS3
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UniProt Splice Variant |
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Entrez Gene |
74100
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UniGene |
Mm.488784
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RefSeq |
XP_006512406
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MGI ID |
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MGI Symbol |
Arpp21
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OMIM |
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CCDS |
CCDS52945
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HPRD |
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IMGT |
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EMBL |
AC100550
AC130551
AF324451
AK002950
AK029467
AK032417
AK032543
AK045507
AK050613
AK137974
BC027107
BC053001
BC128376
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GenPept |
AAH27107
AAH53001
AAK48713
BAC26463
BAC27859
BAC27918
BAC32399
BAC34343
BAE23526
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