Version 5.4
Mus musculus Protein: Ppp1r1c
Summary
InnateDB Protein IDBP-257401.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppp1r1c
Protein Name protein phosphatase 1, regulatory (inhibitor) subunit 1C
Synonyms 4930565M23Rik; 4930579P15Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000107410
InnateDB Gene IDBG-183480 (Ppp1r1c)
Protein Structure
UniProt Annotation
Function Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
Biological Process
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0030307 positive regulation of cell growth
GO:0043086 negative regulation of catalytic activity
GO:0051301 cell division
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1923185
InterPro IPR008466 Protein phosphatase inhibitor, 1DARPP-32
PFAM PF05395
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BKK4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 75276
UniGene Mm.257373
RefSeq NP_001277672
MGI ID
MGI Symbol Ppp1r1c
OMIM
CCDS CCDS71081
HPRD
IMGT
EMBL AK051449 AK051670 AK157871 AL844577 BC120706 BC132149
GenPept AAI20707 AAI32150 BAC34644 BAC34713 BAE34243 CAM14502 CAM14503 CAM14504

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca