Version 5.4
| Mus musculus Protein: Qsox1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-257427.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Qsox1 | ||||||||
| Protein Name | quiescin Q6 sulfhydryl oxidase 1 | ||||||||
| Synonyms | 1300003H02Rik; Qscn6; QSOX; SOx; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000107394 | ||||||||
| InnateDB Gene | IDBG-199929 (Qsox1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Isoform 1: Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.Isoform 2: Secreted. Note=Found in the extracellular medium of quiescent cells but not in proliferating cells.Isoform 3: Secreted. Note=Found in the extracellular medium of quiescent cells but not in proliferating cells.Isoform 4: Secreted. Note=Found in the extracellular medium of quiescent cells but not in proliferating cells. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in the seminal vesicles and skin. {ECO:0000269PubMed:12354420}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1330818 | ||||||||
| InterPro |
IPR012336
Thioredoxin-like fold IPR013766 Thioredoxin domain IPR017905 ERV/ALR sulfhydryl oxidase domain |
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| PFAM |
PF13098
PF13192 PF13462 PF13905 PF00085 PF04777 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8BND5 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 104009 | ||||||||
| UniGene | Mm.475484 | ||||||||
| RefSeq | NP_075757 | ||||||||
| MGI ID | 3T59 | ||||||||
| MGI Symbol | Qsox1 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB044284 AK004880 AK083938 AK149465 AK163119 AK166839 AK169877 AK169920 AK170449 BC034131 BC076590 | ||||||||
| GenPept | AAH34131 AAH76590 BAB21936 BAB23638 BAC39073 BAE28897 BAE37202 BAE39061 BAE41429 BAE41459 BAE41807 | ||||||||