Version 5.4
Mus musculus Protein: Gm4353
Summary
InnateDB Protein IDBP-257453.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gm4353
Protein Name predicted gene 4353
Synonyms 2310006I24Rik; 35kDa; 5330402E05Rik; MP44; NO44;
Species Mus musculus
Ensembl Protein ENSMUSP00000107385
InnateDB Gene IDBG-605081 (Gm4353)
Protein Structure
UniProt Annotation
Function Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nuclear pore complex {ECO:0000250}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Tightly associated with the nuclear membrane and lamina. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
GO:0051028 mRNA transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005643 nuclear pore
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:3782538
InterPro IPR007846 RNA-recognition motif (RRM) Nup35-type domain
IPR017389 Nucleoporin, NUP53
PFAM PF05172
PRINTS
PIRSF PIRSF038119
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R4R6
PhosphoSite PhosphoSite-Q8R4R6
TrEMBL
UniProt Splice Variant
Entrez Gene 69482
UniGene
RefSeq
MGI ID 1WWH
MGI Symbol Gm4353
OMIM
CCDS
HPRD
IMGT
EMBL AF411517 AK009187 AK089997 AK136109 AK145775 AL928869 BC048814
GenPept AAH48814 AAL86380 BAB26128 BAC41034 BAE22825 BAE26644 CAM23081

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca