InnateDB Protein
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IDBP-257762.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Rpgrip1
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Protein Name
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retinitis pigmentosa GTPase regulator interacting protein 1
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Synonyms
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0610005A07Rik; 4930401L23Rik; 4930505G06Rik; A930002K18Rik; AA415034; nmf247;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000107230
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InnateDB Gene
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IDBG-148844 (Rpgrip1)
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Protein Structure
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Function |
Essential for RPGR function and is also required for normal disk morphogenesis. {ECO:0000269PubMed:12651948}.
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Subcellular Localization |
Cell projection, cilium {ECO:0000269PubMed:12651948}. Note=Situated between the axonemal microtubules and the plasma membrane.
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Disease Associations |
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Tissue Specificity |
Colocalizes with RGPR in the photoreceptor connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment. {ECO:0000269PubMed:12140192, ECO:0000269PubMed:12651948}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1932134
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InterPro |
IPR000008
C2 domain
IPR021656
Protein of unknown function DUF3250
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PFAM |
PF00168
PF11618
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PRINTS |
PR00360
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PIRSF |
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SMART |
SM00239
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TIGRFAMs |
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Modification |
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SwissProt |
Q9EPQ2
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PhosphoSite |
PhosphoSite-Q9EPQ2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
77945
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UniGene |
Mm.487226
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RefSeq |
NP_076368
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MGI ID |
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MGI Symbol |
Rpgrip1
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OMIM |
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CCDS |
CCDS36918
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HPRD |
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IMGT |
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EMBL |
AK015037
AK015701
AK029955
AK039097
AY008297
BC016092
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GenPept |
AAG22857
AAH16092
BAB29685
BAB29938
BAC26697
BAC30237
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