Version 5.4
Mus musculus Protein: Fam60a
Summary
InnateDB Protein IDBP-257879.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam60a
Protein Name family with sequence similarity 60, member A
Synonyms Ppcs1; Pptcs1; Tera;
Species Mus musculus
Ensembl Protein ENSMUSP00000107188
InnateDB Gene IDBG-199276 (Fam60a)
Protein Structure
UniProt Annotation
Function Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0030336 negative regulation of cell migration
Cellular Component
GO:0016580 Sin3 complex
Protein Structure and Domains
PDB ID MGI:1929091
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C8M1
PhosphoSite PhosphoSite-Q8C8M1
TrEMBL D3Z1Z9
UniProt Splice Variant
Entrez Gene 56306
UniGene Mm.490705
RefSeq XP_006507136
MGI ID
MGI Symbol Fam60a
OMIM
CCDS CCDS20713
HPRD
IMGT
EMBL AC140327 AK046519 AK145384 AK166569 BC076599 U64033
GenPept AAB09547 AAH76599 BAC32768 BAE26402 BAE38860

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca