InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fam60a

Summary

InnateDB Protein

IDBP-257881.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fam60a

Protein Name

family with sequence similarity 60, member A

Synonyms

Ppcs1; Pptcs1; Tera;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107187

InnateDB Gene

IDBG-199276 (Fam60a)

Protein Structure

UniProt Annotation

Function

Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0030336

negative regulation of cell migration

Cellular Component

GO:0016580

Sin3 complex

Protein Structure and Domains

PDB ID

MGI:1929091

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8C8M1

PhosphoSite

PhosphoSite-Q8C8M1

TrEMBL

D3Z1Z9

UniProt Splice Variant

Entrez Gene

56306

UniGene

Mm.490705

RefSeq

MGI ID

MGI Symbol

Fam60a

OMIM

CCDS

CCDS20713

HPRD

IMGT

EMBL

AC140327 AK046519 AK145384 AK166569 BC076599 U64033

GenPept

AAB09547 AAH76599 BAC32768 BAE26402 BAE38860