Version 5.4
Mus musculus Protein: Agbl2
Summary
InnateDB Protein IDBP-258023.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agbl2
Protein Name ATP/GTP binding protein-like 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000107106
InnateDB Gene IDBG-189658 (Agbl2)
Protein Structure
UniProt Annotation
Function Metallocarboxypeptidase involved in the detyrosination of alpha-tubulin C-terminus. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000269PubMed:17244818}.
Disease Associations
Tissue Specificity Mainly expressed in testis. Also detected in brain, eye, muscle, lung, pancreas, intestine, stomach, pituitary, spleen, adrenal and kidney. Expressed in mitral and granular cells in brain. {ECO:0000269PubMed:17244818}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:2443254
InterPro IPR000834 Peptidase M14, carboxypeptidase A
PFAM PF00246
PRINTS PR00765
PIRSF
SMART SM00631
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CDK2
PhosphoSite PhosphoSite-Q8CDK2
TrEMBL
UniProt Splice Variant
Entrez Gene 271813
UniGene Mm.61146
RefSeq XP_006499692
MGI ID
MGI Symbol Agbl2
OMIM
CCDS CCDS38177
HPRD
IMGT
EMBL AK029744 AK029932 AK030138 AK030182 AK040259 AK079691 AL714026 DQ867026 DQ867027 DQ867028 DQ867029 DQ867030
GenPept ABI51945 ABI51946 ABI51947 ABI51948 ABI51949 BAC26594 BAC26686 BAC26802 BAC26827 BAC30555 BAC37726 CAM20823 CAM20824 CAM20825

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca