Version 5.4
Homo sapiens Protein: UFM1
Summary
InnateDB Protein IDBP-25824.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UFM1
Protein Name ubiquitin-fold modifier 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000239878
InnateDB Gene IDBG-25820 (UFM1)
Protein Structure
UniProt Annotation
Function Ubiquitin-like modifier protein which binds to a number of target proteins, such as DDRGK1. {ECO:0000269PubMed:15071506, ECO:0000269PubMed:20018847}.
Subcellular Localization Nucleus {ECO:0000269PubMed:15071506}. Cytoplasm {ECO:0000269PubMed:15071506}. Note=Predominantly nuclear. Also expressed diffusely in the cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
Experimentally validated
Total 59 [view]
Protein-Protein 56 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0034976 response to endoplasmic reticulum stress
GO:0071569 protein ufmylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR005375 Ubiquitin-fold modifier 1
IPR029071 Ubiquitin-related domain
PFAM PF03671
PRINTS
PIRSF PIRSF038027
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P61960
PhosphoSite PhosphoSite-P61960
TrEMBL
UniProt Splice Variant
Entrez Gene 51569
UniGene Hs.741337
RefSeq NP_057701
HUGO HGNC:20597
OMIM 610553
CCDS CCDS9366
HPRD 15644
IMGT
EMBL AB154404 AF208844 AL356863 BC005193 CR457189 DA664581 Z70222
GenPept AAF64258 AAH05193 BAD15373 CAA94181 CAG33470 CAH70411 CAH70414

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca