Version 5.4
Mus musculus Protein: Rimbp2
Summary
InnateDB Protein IDBP-258329.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rimbp2
Protein Name RIMS binding protein 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000106978
InnateDB Gene IDBG-201689 (Rimbp2)
Protein Structure
UniProt Annotation
Function Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Synaptic plasma membrane. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005886 plasma membrane
GO:0030054 cell junction
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:2443235
InterPro IPR001452 SH3 domain
IPR003961 Fibronectin, type III
IPR011511 Variant SH3 domain
PFAM PF00018
PF14604
PF00041
PF01108
PF07653
PRINTS PR00452
PIRSF
SMART SM00326
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80U40
PhosphoSite PhosphoSite-Q80U40
TrEMBL D3YXR8
UniProt Splice Variant
Entrez Gene 231760
UniGene
RefSeq NP_001074857
MGI ID
MGI Symbol Rimbp2
OMIM
CCDS CCDS39288
HPRD
IMGT
EMBL AC110566 AC111089 AC116715 AK044685 AK122245 BC151100 BC151101
GenPept AAI51101 AAI51102 BAC65527

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca