InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ufc1

Summary

InnateDB Protein

IDBP-258421.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ufc1

Protein Name

ubiquitin-fold modifier conjugating enzyme 1

Synonyms

1110021H02Rik; AA062310; ESTM29;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106933

InnateDB Gene

IDBG-204384 (Ufc1)

Protein Structure

UniProt Annotation

Function

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0071568	UFM1 conjugating enzyme activity

Biological Process

GO:0034976	response to endoplasmic reticulum stress
GO:0071569	protein ufmylation

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1913405

InterPro

IPR014806 Ubiquitin-fold modifier-conjugating enzyme 1
IPR016135 Ubiquitin-conjugating enzyme/RWD-like

PFAM

PF08694

PRINTS

PIRSF

PIRSF008716

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CR09

PhosphoSite

PhosphoSite-Q9CR09

TrEMBL

UniProt Splice Variant

Entrez Gene

66155

UniGene

RefSeq

MGI ID

MGI Symbol

Ufc1

OMIM

CCDS

CCDS15488

HPRD

IMGT

EMBL

AK003070 AK003897 BC021936

GenPept

AAH21936 BAB22546 BAB23063