Version 5.4
Mus musculus Protein: Pom121
Summary
InnateDB Protein IDBP-258694.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pom121
Protein Name nuclear pore membrane protein 121
Synonyms 2610027A18Rik; C80273; mKIAA0618;
Species Mus musculus
Ensembl Protein ENSMUSP00000106801
InnateDB Gene IDBG-203810 (Pom121)
Protein Structure
UniProt Annotation
Function Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL) (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nuclear pore complex {ECO:0000250}. Nucleus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
GO:0051028 mRNA transport
Cellular Component
GO:0005643 nuclear pore
GO:0005789 endoplasmic reticulum membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:2137624
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K3Z9
PhosphoSite PhosphoSite-Q8K3Z9
TrEMBL Q6A036
UniProt Splice Variant
Entrez Gene 107939
UniGene Mm.28399
RefSeq NP_683734
MGI ID
MGI Symbol Pom121
OMIM
CCDS CCDS51662
HPRD
IMGT
EMBL AF516680 AK154473 AK172982 BC053101 CH466529
GenPept AAH53101 AAM64199 BAD32260 BAE32610 EDL19366

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca