InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gnrh1

Summary

InnateDB Protein

IDBP-258850.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gnrh1

Protein Name

gonadotropin releasing hormone 1

Synonyms

Gnrh; Gnrh2; hpg; LHRH; Lhrh1; Lnrh;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106724

InnateDB Gene

IDBG-176259 (Gnrh1)

Protein Structure

UniProt Annotation

Function

Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	2 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005179	hormone activity
GO:0005183	gonadotropin hormone-releasing hormone activity

Biological Process

GO:0007275	multicellular organismal development
GO:0007565	female pregnancy
GO:0010468	regulation of gene expression
GO:0031960	response to corticosteroid
GO:0042698	ovulation cycle
GO:0043066	negative regulation of apoptotic process
GO:0045471	response to ethanol
GO:0048545	response to steroid hormone
GO:2000354	regulation of ovarian follicle development
GO:2001223	negative regulation of neuron migration