Version 5.4
Mus musculus Protein: Tpt1
Summary
InnateDB Protein IDBP-259279.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tpt1
Protein Name tumor protein, translationally-controlled 1
Synonyms p21; p23; TCTP; Trt;
Species Mus musculus
Ensembl Protein ENSMUSP00000106519
InnateDB Gene IDBG-181273 (Tpt1)
Protein Structure
UniProt Annotation
Function Involved in calcium binding and microtubule stabilization. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0009615 response to virus
GO:0019827 stem cell maintenance
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000384 negative regulation of ectoderm development
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005771 multivesicular body
GO:0045298 tubulin complex
Protein Structure and Domains
PDB ID MGI:104890
InterPro IPR011057 Mss4-like
IPR018105 Translationally controlled tumour protein
PFAM PF00838
PRINTS PR01653
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P63028
PhosphoSite PhosphoSite-P63028
TrEMBL D3YU75
UniProt Splice Variant
Entrez Gene 22070
UniGene Mm.474028
RefSeq NP_033455
MGI ID
MGI Symbol Tpt1
OMIM
CCDS CCDS36980
HPRD
IMGT
EMBL AC140244 AK149695 AK150300 AK150500 AK150858 AK151059 AK151266 AK151375 AK151894 AK152690 AK152808 AK159516 AK159565 AK165736 AK166584 AK167413 AK167936 AK168151 AK169730 AY186881 BC092381 X06407
GenPept AAH92381 AAP23875 BAE29032 BAE29452 BAE29613 BAE29913 BAE30076 BAE30253 BAE30347 BAE30778 BAE31421 BAE31513 BAE35146 BAE35188 BAE38361 BAE38873 BAE39502 BAE39940 BAE40116 BAE41334 CAA29697

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca