Version 5.4
Mus musculus Protein: Adap1
Summary
InnateDB Protein IDBP-259344.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Adap1
Protein Name ArfGAP with dual PH domains 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000106489
InnateDB Gene IDBG-206517 (Adap1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0043087 regulation of GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2442201
InterPro IPR001164 Arf GTPase activating protein
IPR001849 Pleckstrin homology domain
PFAM PF01412
PF00169
PRINTS PR00405
PIRSF
SMART SM00105
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8BVR8
UniProt Splice Variant
Entrez Gene 231821
UniGene Mm.297819
RefSeq NP_766311
MGI ID
MGI Symbol Adap1
OMIM
CCDS CCDS19806
HPRD
IMGT
EMBL AC125065 AC161058 AK076768 BC056934 CH466529
GenPept AAH56934 BAC36474 EDL19162

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca