InnateDB Protein
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IDBP-259393.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dcun1d2
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Protein Name
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DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)
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Synonyms
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AW495713; mFLJ10704;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000106464
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InnateDB Gene
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IDBG-134963 (Dcun1d2)
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Protein Structure
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Function |
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8- conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2142792
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InterPro |
IPR005176
Potentiating neddylation domain
IPR009060
UBA-like
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PFAM |
PF03556
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BZJ7
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PhosphoSite |
PhosphoSite-Q8BZJ7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
102323
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UniGene |
Mm.415688
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RefSeq |
NP_001036115
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MGI ID |
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MGI Symbol |
Dcun1d2
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OMIM |
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CCDS |
CCDS40227
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HPRD |
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IMGT |
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EMBL |
AC130818
AK034394
AK155726
BC052676
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GenPept |
BAC28695
BAE33403
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