InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kdelr2

Summary

InnateDB Protein

IDBP-259643.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kdelr2

Protein Name

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

Synonyms

1110007A14Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106359

InnateDB Gene

IDBG-259641 (Kdelr2)

Protein Structure

UniProt Annotation

Function

Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0046923	ER retention sequence binding

Biological Process

GO:0006621	protein retention in ER lumen
GO:0008150	biological_process
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005801	cis-Golgi network
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome