InnateDB Protein
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IDBP-259980.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Rnf170
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Protein Name
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ring finger protein 170
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Synonyms
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6720407G21Rik; AI481227;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000106208
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InnateDB Gene
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IDBG-145210 (Rnf170)
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Protein Structure
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Function |
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. {ECO:0000269PubMed:21610068}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:21610068}; Multi-pass membrane protein {ECO:0000269PubMed:21610068}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1924983
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8CBG9
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PhosphoSite |
PhosphoSite-
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TrEMBL |
D3Z0A0
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UniProt Splice Variant |
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Entrez Gene |
77733
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UniGene |
Mm.468544
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RefSeq |
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MGI ID |
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MGI Symbol |
Rnf170
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC093366
AK036051
AK042063
AK044579
AK080591
AK152760
BC031383
BC114210
BC138930
BC145718
CH466580
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GenPept |
AAH31383
AAI14211
AAI38931
AAI45719
BAC29287
BAC31147
BAC31988
BAC37951
BAE31474
EDL32805
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