Version 5.4
| Mus musculus Protein: Mtif3 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-260004.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Mtif3 | ||||||||
| Protein Name | mitochondrial translational initiation factor 3 | ||||||||
| Synonyms | 2810012L14Rik; AI414549; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000106193 | ||||||||
| InnateDB Gene | IDBG-208951 (Mtif3) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. {ECO:0000250}. | ||||||||
| Subcellular Localization | Mitochondrion {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1923616 | ||||||||
| InterPro |
IPR001288
Translation initiation factor 3 IPR019814 Translation initiation factor 3, N-terminal IPR019815 Translation initiation factor 3, C-terminal |
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| PFAM |
PF05198
PF00707 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9CZD5 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | D3Z0H9 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 76366 | ||||||||
| UniGene | Mm.486234 | ||||||||
| RefSeq | |||||||||
| MGI ID | 2CRQ | ||||||||
| MGI Symbol | Mtif3 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS19874 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC124828 AK012733 AK147090 AL513345 BC052439 BC115684 BC115685 CH466614 | ||||||||
| GenPept | AAH52439 AAI15685 AAI15686 BAB28438 BAE27670 EDL05823 | ||||||||