InnateDB Protein
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IDBP-260103.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mtus2
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Protein Name
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microtubule associated tumor suppressor candidate 2
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Synonyms
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5730592G18Rik; A730013O20Rik; AU067634; C130038G02Rik; Cazip; Gm763; mKIAA0774;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000106144
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InnateDB Gene
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IDBG-209191 (Mtus2)
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Protein Structure
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Function |
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton. Note=Associated with the microtubule network at the growing distal tip (the plus- end) of microtubules. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in heart from early embryonic development onwards. Later during embryonic development, expressed in brain and nervous system, in limb buds and in the epithelium lining the bronchia of the lung. Detected in adult brain, heart and eye, but not detected in other adult tissues examined. {ECO:0000269PubMed:19806667}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
11 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915388
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3UHD3
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PhosphoSite |
PhosphoSite-Q3UHD3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
77521
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UniGene |
Mm.407843
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RefSeq |
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MGI ID |
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MGI Symbol |
Mtus2
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AB093263
AK019985
AK147457
BC055016
BC150942
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GenPept |
AAH55016
AAI50943
BAB31952
BAC41447
BAE27924
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