Mus musculus Protein: Hist1h2bp | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-260209.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Hist1h2bp | ||||||||
Protein Name | histone cluster 1, H2bp | ||||||||
Synonyms | |||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000106099 | ||||||||
InnateDB Gene | IDBG-134499 (Hist1h2bp) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||||||||
Subcellular Localization | Nucleus. Chromosome. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | |||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | MGI:2448409 | ||||||||
InterPro |
IPR000558
Histone H2B IPR003958 Transcription factor CBF/NF-Y/archaeal histone IPR007125 Histone core IPR009072 Histone-fold |
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PFAM |
PF00808
PF00125 |
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PRINTS |
PR00621
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PIRSF | |||||||||
SMART |
SM00427
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TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | Q8CGP2 | ||||||||
PhosphoSite | PhosphoSite-Q8CGP2 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 319188 | ||||||||
UniGene | Mm.277425 | ||||||||
RefSeq | NP_835509 | ||||||||
MGI ID | |||||||||
MGI Symbol | Hist1h2bp | ||||||||
OMIM | |||||||||
CCDS | CCDS26298 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AL589651 AY158930 BC061044 M25487 | ||||||||
GenPept | AAA50377 AAH61044 AAO06240 CAI24115 CAI24116 | ||||||||