Version 5.4
Mus musculus Protein: Lrp12
Summary
InnateDB Protein IDBP-260561.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lrp12
Protein Name low density lipoprotein-related protein 12
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000105934
InnateDB Gene IDBG-137310 (Lrp12)
Protein Structure
UniProt Annotation
Function Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Membrane, coated pit {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006897 endocytosis
GO:0008150 biological_process
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0005905 coated pit
Protein Structure and Domains
PDB ID MGI:2443132
InterPro IPR000859 CUB domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
PFAM PF00431
PF00057
PRINTS PR00261
PIRSF
SMART SM00042
SM00192
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BUJ9
PhosphoSite PhosphoSite-Q8BUJ9
TrEMBL
UniProt Splice Variant
Entrez Gene 239393
UniGene Mm.39874
RefSeq XP_006520966
MGI ID
MGI Symbol Lrp12
OMIM
CCDS
HPRD
IMGT
EMBL AK050512 AK084675 BC058345
GenPept AAH58345 BAC34299 BAC39247

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca