InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc25a42

Summary

InnateDB Protein

IDBP-260932.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc25a42

Protein Name

solute carrier family 25, member 42

Synonyms

2900084M01Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105754

InnateDB Gene

IDBG-162159 (Slc25a42)

Protein Structure

UniProt Annotation

Function

Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'- diphosphate. {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005347	ATP transmembrane transporter activity
GO:0015217	ADP transmembrane transporter activity
GO:0015228	coenzyme A transmembrane transporter activity
GO:0043262	adenosine-diphosphatase activity
GO:0080122	AMP transmembrane transporter activity

Biological Process

GO:0008152	metabolic process
GO:0015866	ADP transport
GO:0015867	ATP transport
GO:0035349	coenzyme A transmembrane transport
GO:0080121	AMP transport

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1920345

InterPro

IPR002067 Mitochondrial carrier protein
IPR002167 Graves disease carrier protein
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain

PFAM

PF00153

PRINTS

PR00926
PR00928

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8R0Y8